Title : PHF6 and JAK3 mutations cooperate to drive T-cell acute lymphoblastic leukemia progression.

Pub. Date : 2022 Feb

PMID : 34465864






1 Functional Relationships(s)
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1 We subsequently found that Phf6 deficiency promotes JAK3M511I-induced T-ALL progression in mice by inhibiting the Bai1-Mdm2-P53 signaling pathway, which is independent of the JAK3/STAT5 signaling pathway. phf6 adhesion G protein-coupled receptor B1 Mus musculus