Pub. Date : 2021 Oct
PMID : 34461095
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Here, we demonstrate that the prefusion-stabilized two-proline "S2P" spike -widely employed for laboratory work and clinical studies- unfolds when stored at 4 C, physiological pH, as observed by electron microscopy (EM) and differential scanning calorimetry, but that its trimeric, native-like conformation can be reacquired by low pH treatment. | Proline | surface glycoprotein | Severe acute respiratory syndrome coronavirus 2 |