Title : MiR-148a-3p Regulates the Invasion and Odontoblastic Differentiation of Human Dental Pulp Stem Cells via the Wnt1/β-Catenin Pathway.

Pub. Date : 2021 Nov 30

PMID : 34456188






3 Functional Relationships(s)
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1 MiR-148a-3p mimic and siWnt1 suppressed the cell viability, invasion, and odontoblastic differentiation of hDPSCs and inhibited the Wnt1, beta-catenin, DSPP, DMP-1, RUNX2, OCN, and Smad4 expressions. mir-148a-3p Wnt family member 1 Homo sapiens
2 Also, miR-148a-3p mimic and inhibitor reversed the effects of Wnt1 overexpression and siWnt1. mir-148a-3p Wnt family member 1 Homo sapiens
3 Conclusions: MiR-148a-3p modulated the invasion and odontoblastic differentiation of hDPSCs through the Wnt1/beta-catenin pathway. mir-148a-3p Wnt family member 1 Homo sapiens