Pub. Date : 2021 Aug 13
PMID : 34443492
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Compared to nontreated cachectic mice, in LC-cachexia + curcumin and LC-cachexia + resveratrol groups, body and muscle weights (gastrocnemius), limb muscle strength, muscle damage, and myofiber cross-sectional area improved, and in both muscles, sirtuin-1 increased, while proteolysis (troponin I), proteolytic markers, and signaling pathways were attenuated. | Resveratrol | sirtuin 1 | Mus musculus |
2 | Curcumin and resveratrol elicited beneficial effects on fast- and slow-twitch limb muscle phenotypes in cachectic mice through sirtuin-1 activation, attenuation of atrophy signaling pathways, and proteolysis in cancer cachectic mice. | Resveratrol | sirtuin 1 | Mus musculus |