Pub. Date : 2021 Aug 2
PMID : 34442729
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Here, we discovered that proline oxidation, catalyzed by the proline oxidase Put1, a mitochondrial flavin-dependent enzyme converting proline into 1-pyrroline-5-carboxylate, controls the chronological lifespan of the yeast Saccharomyces cerevisiae. | Proline | proline dehydrogenase | Saccharomyces cerevisiae S288C |
| 2 | Here, we discovered that proline oxidation, catalyzed by the proline oxidase Put1, a mitochondrial flavin-dependent enzyme converting proline into 1-pyrroline-5-carboxylate, controls the chronological lifespan of the yeast Saccharomyces cerevisiae. | Proline | proline dehydrogenase | Saccharomyces cerevisiae S288C |
| 3 | More importantly, the oxidation of proline by Put1 helped maintain the mitochondrial membrane potential and ATP production through the aging period. | Proline | proline dehydrogenase | Saccharomyces cerevisiae S288C |