Title : Metformin Decreases 2-HG Production through the MYC-PHGDH Pathway in Suppressing Breast Cancer Cell Proliferation.

Pub. Date : 2021 Jul 26

PMID : 34436421






2 Functional Relationships(s)
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1 Metformin Decreases 2-HG Production through the MYC-PHGDH Pathway in Suppressing Breast Cancer Cell Proliferation. Metformin MYC proto-oncogene, bHLH transcription factor Homo sapiens
2 We also showed that metformin"s inhibitory effect on the PHGDH-2HG axis may occur through the regulation of the AMPK-MYC pathway. Metformin MYC proto-oncogene, bHLH transcription factor Homo sapiens