Title : Lockdown of mitochondrial Ca2+ extrusion and subsequent resveratrol treatment kill HeLa cells by Ca2+ overload.

Pub. Date : 2021 Oct

PMID : 34428589






1 Functional Relationships(s)
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1 This therapeutic approach using siNCLX mediated gene silencing and drug therapy with resveratrol indicates the disruption of calcium homeostasis, increase in caspase (-3, 8, 9) mRNA expressions and DNA damage leading to apoptotic cell death. Resveratrol caspase 3 Homo sapiens