Title : Naringin and Hesperidin Counteract Diclofenac-Induced Hepatotoxicity in Male Wistar Rats via Their Antioxidant, Anti-Inflammatory, and Antiapoptotic Activities.

Pub. Date : 2021

PMID : 34422219






1 Functional Relationships(s)
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1 The administrations of naringin and hesperidin to diclofenac-injected rats led to a significant decrease in the elevated serum ALT, AST, LDH, ALP, GGT, total bilirubin, TNF-alpha, and IL-17 levels as well as liver lipid peroxidation and liver p53 and caspase-3 mRNA expressions. naringin Wistar clone pR53P1 p53 pseudogene Rattus norvegicus