Title : 6β-Hydroxytestosterone Promotes Angiotensin II-Induced Hypertension via Enhanced Cytosolic Phospholipase A2α Activity.

Pub. Date : 2021 Sep

PMID : 34420370






1 Functional Relationships(s)
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1 Antagonists of prostaglandin E2-EP1/EP3 receptors and thromboxane A2-TP receptors decreased the effect of 6beta-hydroxytestosterone in restoring the angiotensin II-induced increase in systolic blood pressure, cardiac and renal collagen deposition, and reactive oxygen species production in cPLA2alpha+/+/Cyp1b1-/- mice. Dinoprostone prostaglandin E receptor 3 (subtype EP3) Mus musculus