Title : Design, synthesis and analysis of novel sphingosine kinase-1 inhibitors to improve oral bioavailability.

Pub. Date : 2021 Oct 15

PMID : 34418572






1 Functional Relationships(s)
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1 A set of compounds designed to assess the impact of synthetic modifications to the hydroxynaphthalene ring region of the template inhibitor with SK1 to obtain a compound with increased efficacy in vivo. Naphthols sphingosine kinase 1 Homo sapiens