Title : Novel ι-Carrageenan Tetrasaccharide Alleviates Liver Lipid Accumulation via the Bile Acid-FXR-SHP/PXR Pathway to Regulate Cholesterol Conversion and Fatty Acid Metabolism in Insulin-Resistant Mice.

Pub. Date : 2021 Sep 1

PMID : 34415766






1 Functional Relationships(s)
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1 Western blot analysis showed that iotaCTs downregulated hepatic FXR and small heterodimer partner (SHP) expression and increased downstream CYP7A1 expression via regulating the FXR-SHP signal to accelerate liver cholesterol conversion. Cholesterol cytochrome P450, family 7, subfamily a, polypeptide 1 Mus musculus