Pub. Date : 2021 Aug 12
PMID : 34413963
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Among 46 analogues tested, compounds 21, 30, and 33 displayed high activities against asexual blood stage parasites (PfNF54 IC50 = 0.025-0.043 muM), whereas amide compound 46 additionally showed activity against late-stage gametocytes (stage IV/V; PfLG IC50 = 0.6 +- 0.1 muM) and 860-fold higher selectivity over hERG (46, SI = 43) compared to AST. | Amides | ETS transcription factor ERG | Homo sapiens |