Title : The flavonoid Astragalin shows anti-tumor activity and inhibits PI3K/AKT signaling in gastric cancer.

Pub. Date : 2021 Nov

PMID : 34396710






3 Functional Relationships(s)
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1 The flavonoid Astragalin shows antitumor activity and inhibits PI3K/AKT signaling in gastric cancer. astragalin thymoma viral proto-oncogene 1 Mus musculus
2 In addition, Astragalin induced the expression of apoptotic signaling proteins, suppressed the migration and invasion cancer cells, and inhibited the PI3K/AKT signaling pathway significantly. astragalin thymoma viral proto-oncogene 1 Mus musculus
3 In conclusion, Astragalin exerts its anti-cancer activities through inhibiting PI3K/AKT signaling, which highlights its potential for the treatment of gastric cancer. astragalin thymoma viral proto-oncogene 1 Mus musculus