Pub. Date : 2021 Oct
PMID : 34392176
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In this framework, we have developed in recent years a family of benzofuran compounds that act as Hsp90 allosteric modulators. | benzofuran | heat shock protein 90 alpha family class A member 1 | Homo sapiens |
| 2 | Western blotting, DARTS (i.e., Drug Affinity Responsive Target Stability) and enzymatic assays data confirmed a dose-dependent interaction of MDH2 with several members of the benzofuran Hsp90 modulators family and a computational model allowed to interpret the observed interactions. | benzofuran | heat shock protein 90 alpha family class A member 1 | Homo sapiens |