Title : Metformin attenuates renal tubulointerstitial fibrosis via upgrading autophagy in the early stage of diabetic nephropathy.

Pub. Date : 2021 Aug 11

PMID : 34381133






1 Functional Relationships(s)
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1 Metformin-induced AMPK significantly ameliorated renal autophagic function, inhibited the partial EMT of RTECs, and attenuated TIF, all of which effectively prevented or delayed the onset of DN. Metformin protein kinase AMP-activated catalytic subunit alpha 2 Rattus norvegicus