Pub. Date : 2021
PMID : 34377256
8 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Effect of miR-132-3p on sepsis-induced acute kidney injury in mice via regulating HAVCR1/KIM-1. | mir-132-3p | hepatitis A virus cellular receptor 1 | Mus musculus |
| 2 | Effect of miR-132-3p on sepsis-induced acute kidney injury in mice via regulating HAVCR1/KIM-1. | mir-132-3p | hepatitis A virus cellular receptor 1 | Mus musculus |
| 3 | Dual-luciferase reporter assay was performed to verify the targeting relationship between miR-132-3p and HAVCR1/KIM-1. | mir-132-3p | hepatitis A virus cellular receptor 1 | Mus musculus |
| 4 | Dual-luciferase reporter assay was performed to verify the targeting relationship between miR-132-3p and HAVCR1/KIM-1. | mir-132-3p | hepatitis A virus cellular receptor 1 | Mus musculus |
| 5 | MiR-132-3p overexpression could improve the renal function of the mice with sepsis and inhibit renal cell apoptosis and inflammatory progression, whereas HAVCR1/KIM1 overexpression exhibited an opposite effect and could block the renal protective effects of miR-132-3p overexpression on the septic mice. | mir-132-3p | hepatitis A virus cellular receptor 1 | Mus musculus |
| 6 | MiR-132-3p overexpression could improve the renal function of the mice with sepsis and inhibit renal cell apoptosis and inflammatory progression, whereas HAVCR1/KIM1 overexpression exhibited an opposite effect and could block the renal protective effects of miR-132-3p overexpression on the septic mice. | mir-132-3p | hepatitis A virus cellular receptor 1 | Mus musculus |
| 7 | CONCLUSION: MiR-132-3p overexpression can inhibit renal cell apoptosis and inflammatory progression via suppressing HAVCR1/KIM-1 expression, thereby exert renal protective effects on mice with sepsis. | mir-132-3p | hepatitis A virus cellular receptor 1 | Mus musculus |
| 8 | CONCLUSION: MiR-132-3p overexpression can inhibit renal cell apoptosis and inflammatory progression via suppressing HAVCR1/KIM-1 expression, thereby exert renal protective effects on mice with sepsis. | mir-132-3p | hepatitis A virus cellular receptor 1 | Mus musculus |