Title : A mesenchymal-like subpopulation in non-neuroendocrine SCLC contributes to metastasis.

Pub. Date : 2021 Jul 20

PMID : 34373217






1 Functional Relationships(s)
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1 Importantly, inhibition of the TGF-beta signaling through ectopic expression of dominant-negative Tgfbr2 (Tgfbr2-DN) or treatment with Tgfbr1 inhibitor SD-208 consistently abrogated tumor metastasis in nude mouse allograft assays. SD-208 transforming growth factor, beta receptor I Mus musculus