Title : Caffeine Has Different Immunomodulatory Effect on the Cytokine Expression and NLRP3 Inflammasome Function in Various Human Macrophage Subpopulations.

Pub. Date : 2021 Jul 14

PMID : 34371919






1 Functional Relationships(s)
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1 We showed that caffeine (1) altered adenosine receptor expression, (2) changed Akt/AMPK/mTOR signaling pathways, and (3) inhibited STAT1/IL-10 signaling axis in M-MPhis. Caffeine AKT serine/threonine kinase 1 Homo sapiens