Title : Single-Cell RNA Sequencing Supports Preferential Bioactivation of Remdesivir in the Liver.

Pub. Date : 2021 Sep 17

PMID : 34370586






2 Functional Relationships(s)
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1 titled, "Key Metabolic Enzymes in Remdesivir Activation in Lung Cells," validates the canonical McGuigan enzymes (CES1, CTSA, HINT1) involved in remdesivir"s (RDV"s) bioactivation using bioinformatic and biochemical approaches (1)..... remdesivir cathepsin A Homo sapiens
2 titled, "Key Metabolic Enzymes in Remdesivir Activation in Lung Cells," validates the canonical McGuigan enzymes (CES1, CTSA, HINT1) involved in remdesivir"s (RDV"s) bioactivation using bioinformatic and biochemical approaches (1)..... remdesivir cathepsin A Homo sapiens