Title : Identification of Potential Binding Sites of Sialic Acids on the RBD Domain of SARS-CoV-2 Spike Protein.

Pub. Date : 2021

PMID : 34368076






4 Functional Relationships(s)
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1 Identification of Potential Binding Sites of Sialic Acids on the RBD Domain of SARS-CoV-2 Spike Protein. Sialic Acids surface glycoprotein Severe acute respiratory syndrome coronavirus 2
2 SARS-CoV-2 shares similar sequences of the spike protein with the Middle East Respiratory Syndrome Coronavirus (MERS-CoV), which can invade host cells by binding to either DPP4 or sialic acids. Sialic Acids surface glycoprotein Severe acute respiratory syndrome coronavirus 2
3 This study shows that sialic acids can moderately interact with the spike protein of SARS-CoV-2 by binding between the two RBDs of the spike protein, indicating it could be a potential secondary or auxiliary receptor of SARS-CoV-2. Sialic Acids surface glycoprotein Severe acute respiratory syndrome coronavirus 2
4 This study shows that sialic acids can moderately interact with the spike protein of SARS-CoV-2 by binding between the two RBDs of the spike protein, indicating it could be a potential secondary or auxiliary receptor of SARS-CoV-2. Sialic Acids surface glycoprotein Severe acute respiratory syndrome coronavirus 2