Title : Differences in MPS I and MPS II Disease Manifestations.

Pub. Date : 2021 Jul 23

PMID : 34360653






4 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 In MPS II, the first step of degradation of heparan sulfate (HS) and dermatan sulfate (DS) is blocked by a deficiency in the lysosomal enzyme iduronate 2-sulfatase (IDS), while, in MPS I, blockage of the second step is caused by a deficiency in iduronidase (IDUA). Heparitin Sulfate iduronate 2-sulfatase Homo sapiens
2 In MPS II, the first step of degradation of heparan sulfate (HS) and dermatan sulfate (DS) is blocked by a deficiency in the lysosomal enzyme iduronate 2-sulfatase (IDS), while, in MPS I, blockage of the second step is caused by a deficiency in iduronidase (IDUA). Heparitin Sulfate iduronate 2-sulfatase Homo sapiens
3 In MPS II, the first step of degradation of heparan sulfate (HS) and dermatan sulfate (DS) is blocked by a deficiency in the lysosomal enzyme iduronate 2-sulfatase (IDS), while, in MPS I, blockage of the second step is caused by a deficiency in iduronidase (IDUA). Heparitin Sulfate iduronate 2-sulfatase Homo sapiens
4 In MPS II, the first step of degradation of heparan sulfate (HS) and dermatan sulfate (DS) is blocked by a deficiency in the lysosomal enzyme iduronate 2-sulfatase (IDS), while, in MPS I, blockage of the second step is caused by a deficiency in iduronidase (IDUA). Heparitin Sulfate iduronate 2-sulfatase Homo sapiens