Pub. Date : 2021 Aug 2
PMID : 34340703
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Despite its severe adverse effects, selinexor, a selective first-in-class inhibitor of the common nuclear export receptor XPO1, was developed to target nucleocytoplasmic protein shuttling and received accelerated FDA approval in 2019 in combination with dexamethasone as a fifth-line therapeutic option for adults with relapsed refractory multiple myeloma (RRMM). | selinexor | exportin 1 | Mus musculus |