Title : PSPC1 is a new contextual determinant of aberrant subcellular translocation of oncogenes in tumor progression.

Pub. Date : 2021 Aug 2

PMID : 34340703






1 Functional Relationships(s)
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1 Despite its severe adverse effects, selinexor, a selective first-in-class inhibitor of the common nuclear export receptor XPO1, was developed to target nucleocytoplasmic protein shuttling and received accelerated FDA approval in 2019 in combination with dexamethasone as a fifth-line therapeutic option for adults with relapsed refractory multiple myeloma (RRMM). selinexor exportin 1 Mus musculus