Title : Discovery of small molecule acting as multitarget inhibitor of colorectal cancer by simultaneous blocking of the key COX-2, 5-LOX and PIM-1 kinase enzymes.

Pub. Date : 2021 Oct

PMID : 34303896






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Compounds 5a-d and 5g displayed inhibitory activity against COX-2 nearly equal to Celecoxib with high selectivity index (SI). Celecoxib mitochondrially encoded cytochrome c oxidase II Homo sapiens