Title : Melanoidins, extracted from Chinese traditional vinegar powder, inhibit alcohol-induced inflammation and oxidative stress in macrophages via activation of SIRT1 and SIRT3.

Pub. Date : 2021 Sep 7

PMID : 34286801






3 Functional Relationships(s)
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1 In macrophages, melanoidins significantly suppress the mRNA expression of interleukin (Il)-6, Il-1beta and tumor necrosis factor alpha (Tnf-alpha) with a concomitant inhibitory effect on IL-1beta, IL-6 and TNFalpha secretion, which are increased by ethanol. Ethanol tumor necrosis factor Homo sapiens
2 In macrophages, melanoidins significantly suppress the mRNA expression of interleukin (Il)-6, Il-1beta and tumor necrosis factor alpha (Tnf-alpha) with a concomitant inhibitory effect on IL-1beta, IL-6 and TNFalpha secretion, which are increased by ethanol. Ethanol tumor necrosis factor Homo sapiens
3 In macrophages, melanoidins significantly suppress the mRNA expression of interleukin (Il)-6, Il-1beta and tumor necrosis factor alpha (Tnf-alpha) with a concomitant inhibitory effect on IL-1beta, IL-6 and TNFalpha secretion, which are increased by ethanol. Ethanol tumor necrosis factor Homo sapiens