Title : Identification of kinase inhibitors that rule out the CYP27B1-mediated activation of vitamin D: an integrated machine learning and structure-based drug designing approach.

Pub. Date : 2021 Aug

PMID : 34272637






1 Functional Relationships(s)
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1 Tyrosine kinase inhibitor such as imatinib is reported to interfere with the activation of vitamin D3 by inhibiting CYP27B1 enzyme. Cholecalciferol cytochrome P450 family 27 subfamily B member 1 Homo sapiens