Title : PD-L1 expression in tumor cells is associated with a favorable prognosis in patients with high-risk endometrial cancer.

Pub. Date : 2021 Sep

PMID : 34272092






4 Functional Relationships(s)
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1 RESULTS: Positive PD-L1 staining in TCs (>=1%), ICs (>=1%), and in combination (CPS >=1) was detected in 14.0%, 37.3%, and 45.1% of the samples, respectively. 9-ethyl-N-(3,4,5-trimethoxyphenyl)carbazole-3-sulfonamide CD274 molecule Homo sapiens
2 PD-L1 positivity in TCs was more frequent in high-grade than in low-grade tumors, while that in ICs was associated with lymphovascular space invasion, non-endometrioid histology, and deep myometrial invasion. 9-ethyl-N-(3,4,5-trimethoxyphenyl)carbazole-3-sulfonamide CD274 molecule Homo sapiens
3 PD-L1 expression in both TCs and ICs was more frequent in POLE ultramutated and MMR-deficient subtypes than in p53-mutant and NSMP subtypes. 9-ethyl-N-(3,4,5-trimethoxyphenyl)carbazole-3-sulfonamide CD274 molecule Homo sapiens
4 PD-L1 positivity in TCs, but not in ICs or combined (CPS), was associated with a favorable prognosis in patients with high-risk endometrial cancer. 9-ethyl-N-(3,4,5-trimethoxyphenyl)carbazole-3-sulfonamide CD274 molecule Homo sapiens