Title : Lithocholic Acid Activates Mas-Related G Protein-Coupled Receptors, Contributing to Itch in Mice.

Pub. Date : 2022 Jan 1

PMID : 34263729






1 Functional Relationships(s)
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1 Moreover, treatment with QWF (an antagonist of Mrgpra1 and Mrgprb2), YM254890 (Galphaq inhibitor), and U73122 (an inhibitor of phospholipase C) significantly suppressed the LCA-induced responses, implying that the LCA-induced responses are indeed mediated by Mrgpra1 and Mrgprb2. YM-254890 MAS-related GPR, member B2 Mus musculus