Title : Diosmetin has therapeutic efficacy in colitis regulating gut microbiota, inflammation, and oxidative stress via the circ-Sirt1/Sirt1 axis.

Pub. Date : 2022 Apr

PMID : 34262136






1 Functional Relationships(s)
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1 Furthermore, we demonstrated that diosmetin markedly increased the expression of Nrf2 and HO-1 and reduced the ratio of acetylated NF-kappaB and NF-kappaB by activating the circ-Sirt1/Sirt1 axis, which inhibited oxidative stress and inflammation in vivo and in vitro. diosmetin nuclear factor, erythroid derived 2, like 2 Mus musculus