Title : Allicin Reduces 5-fluorouracil-resistance in Gastric Cancer Cells through Modulating MDR1, DKK1, and WNT5A Expression.

Pub. Date : 2021 Oct

PMID : 34261152






2 Functional Relationships(s)
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1 Indeed, the combination of allicin and 5-FU significantly decreased the expression of the P-gp and CD44 proteins (P<0.05). Fluorouracil CD44 molecule (Indian blood group) Homo sapiens
2 CONCLUSION: Our findings indicate that the combination of allicin with 5-FU could reverse multidrug resistance in the GC cells by reducing the expression of WNT5A, DKK1, MDR1, P-gp, and CD44 levels. Fluorouracil CD44 molecule (Indian blood group) Homo sapiens