Title : Recognition of N6-Methyladenosine by the YTHDC1 YTH Domain Studied by Molecular Dynamics and NMR Spectroscopy: The Role of Hydration.

Pub. Date : 2021 Jul 22

PMID : 34258996






1 Functional Relationships(s)
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1 The YTHDC1"s preference for the 5"-Gm6A-3" motif is partially facilitated by a network of water-mediated interactions between the 2-amino group of the guanosine and residues in the m6A binding pocket. Water YTH domain containing 1 Homo sapiens