Title : Pterostilbene inhibits hepatocellular carcinoma proliferation and HBV replication by targeting ribonucleotide reductase M2 protein.

Pub. Date : 2021

PMID : 34249439






2 Functional Relationships(s)
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1 Pterostilbene, a natural plant component, potently inhibited in vitro RR enzyme activity with the IC50 of about 0.62 muM through interacting with RRM2 protein, which was much higher than current RRM2 inhibitory drugs. pterostilbene ribonucleotide reductase M2 Mus musculus
2 This study demonstrates that pterostilbene is a novel potent RR inhibitor by targeting RRM2. pterostilbene ribonucleotide reductase M2 Mus musculus