Title : Transfer of miRNA in tumor-derived exosomes suppresses breast tumor cell invasion and migration by inducing M1 polarization in macrophages.

Pub. Date : 2021 Oct 1

PMID : 34245773






1 Functional Relationships(s)
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1 Delivery of miR-130 into macrophages resulted in upregulation of M1 specific markers and cytokines, including CD86, Irf5, Nos2, TNF-alpha, and IL-1beta and downregulation of M2 specific markers and cytokines, including CD206, Ym1, Arg, TGF-beta, and IL-10. mir-130 mannose receptor, C type 1 Mus musculus