Title : Age-dependent alterations in key components of the nigrostriatal dopaminergic system and distinct motor phenotypes.

Pub. Date : 2022 Apr

PMID : 34244603






4 Functional Relationships(s)
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1 However, it is unknown whether dSNc and vSNc DA neurons and striatal DA terminals age in similar patterns, and whether these changes parallel motor deficits. Dopamine renin binding protein Homo sapiens
2 But depolarization-evoked firing in vSNc DA neurons increased with age. Dopamine renin binding protein Homo sapiens
3 In the dorsal striatum, dopamine release declined with age. Dopamine renin binding protein Homo sapiens
4 Therefore, key components in the nigrostriatal DA system exhibit distinct aging patterns and may contribute to age-related alterations in locomotion and coordination. Dopamine renin binding protein Homo sapiens