Title : Prokineticin-2 prevents neuronal cell deaths in a model of traumatic brain injury.

Pub. Date : 2021 Jul 9

PMID : 34244497






1 Functional Relationships(s)
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1 We show that Prok2 prevents neuronal cell death by suppressing the biosynthesis of lipid peroxidation substrates, arachidonic acid-phospholipids, via accelerated F-box only protein 10 (Fbxo10)-driven ubiquitination, degradation of long-chain-fatty-acid-CoA ligase 4 (Acsl4), and inhibition of lipid peroxidation. Phospholipids prokineticin 2 Mus musculus