Pub. Date : 2021 Jul 9
PMID : 34243689
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Affinity of phytoconstituents towards SARS-CoV-2 spike protein-human ACE2 complex decreased as isomeldenin > tinosporaside > EGCG whereas in case of unbound ACE2, the strength of binding followed the order isomeldenin > tinosporaside > ellagic acid. | epigallocatechin gallate | surface glycoprotein | Severe acute respiratory syndrome coronavirus 2 |
2 | SAR analysis revealed that isomeldenin, tinosporaside, EGCG and ellagic acid bind to viral spike glycoproteins via H-bond, Pi-Pi, Pi-sigma and Pi-alkyl type interactions. | epigallocatechin gallate | surface glycoprotein | Severe acute respiratory syndrome coronavirus 2 |