Title : Metabolic Enzyme DLST Promotes Tumor Aggression and Reveals a Vulnerability to OXPHOS Inhibition in High-Risk Neuroblastoma.

Pub. Date : 2021 Sep 1

PMID : 34233924






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 DLST is an E2 component of the a-ketoglutarate (a-KG) dehydrogenase complex, which governs the entry of glutamine into the tricarboxylic acid cycle (TCA) for oxidative decarboxylation. Tricarboxylic Acids dihydrolipoamide S-succinyltransferase Homo sapiens