Title : MCIR1: A patient-derived mantle cell lymphoma line for discovering new treatments for ibrutinib resistance.

Pub. Date : 2021 Oct

PMID : 34214199






1 Functional Relationships(s)
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1 RESULTS: We show that MCIR1 is a bona fide ibrutinib-resistant MCL cell line with normal BTK-/PLCgamma2 but ibrutinib-resistant ERK1/2 and AKT1 signaling. ibrutinib AKT serine/threonine kinase 1 Homo sapiens