Pub. Date : 2021 Jun 30
PMID : 34208928
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Based on docking experiments driven by experimental evidence, we propose a non-covalent mechanism for Mpro inhibition in which a hydrogen bond between the selenium atom and Gln189 residue in the catalytic pocket could explain the higher Mpro activity of 2d and, as a result, its better antiviral profile. | Selenium | NEWENTRY | Severe acute respiratory syndrome-related coronavirus |
2 | Based on docking experiments driven by experimental evidence, we propose a non-covalent mechanism for Mpro inhibition in which a hydrogen bond between the selenium atom and Gln189 residue in the catalytic pocket could explain the higher Mpro activity of 2d and, as a result, its better antiviral profile. | Selenium | NEWENTRY | Severe acute respiratory syndrome-related coronavirus |