Title : Hydroquinone Induces NLRP3-Independent IL-18 Release from ARPE-19 Cells.

Pub. Date : 2021 Jun 6

PMID : 34204067






3 Functional Relationships(s)
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Protein Name
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1 Hydroquinone Induces NLRP3-Independent IL-18 Release from ARPE-19 Cells. hydroquinone NLR family pyrin domain containing 3 Homo sapiens
2 Cytoplasmic NLRP3 levels increased after the hydroquinone treatment of IL-1alpha-primed RPE cells, but IL-18 was equally released from primed and nonprimed cells. hydroquinone NLR family pyrin domain containing 3 Homo sapiens
3 Collectively, hydroquinone caused DNA damage seen as reduced intracellular PARP levels and induced NLRP3-independent IL-18 secretion in human RPE cells. hydroquinone NLR family pyrin domain containing 3 Homo sapiens