Pub. Date : 2021 Jun 6
PMID : 34204067
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Hydroquinone Induces NLRP3-Independent IL-18 Release from ARPE-19 Cells. | hydroquinone | NLR family pyrin domain containing 3 | Homo sapiens |
2 | Cytoplasmic NLRP3 levels increased after the hydroquinone treatment of IL-1alpha-primed RPE cells, but IL-18 was equally released from primed and nonprimed cells. | hydroquinone | NLR family pyrin domain containing 3 | Homo sapiens |
3 | Collectively, hydroquinone caused DNA damage seen as reduced intracellular PARP levels and induced NLRP3-independent IL-18 secretion in human RPE cells. | hydroquinone | NLR family pyrin domain containing 3 | Homo sapiens |