Title : Crystal structure of human brain-type fatty acid-binding protein FABP7 complexed with palmitic acid.

Pub. Date : 2021 Jul 1

PMID : 34196621






8 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Crystal structure of human brain-type fatty acid-binding protein FABP7 complexed with palmitic acid. Fatty Acids fatty acid binding protein 7 Homo sapiens
2 The brain-type fatty acid-binding protein FABP7, which is expressed in astrocytes and neural progenitors, is a member of the intracellular lipid-binding protein family. Fatty Acids fatty acid binding protein 7 Homo sapiens
3 Structures of unsaturated fatty acids, such as oleic acid (OA) and docosahexaenoic acid (DHA), bound to FABP7 have been elucidated; however, structures of saturated fatty acids bound to FABP7 remain unknown. Fatty Acids fatty acid binding protein 7 Homo sapiens
4 To better understand fatty acid recognition, here the crystal structure of human brain-type fatty acid-binding protein FABP7 complexed with palmitic acid (PA), a saturated fatty acid, is reported at a resolution of 1.6 A. Fatty Acids fatty acid binding protein 7 Homo sapiens
5 To better understand fatty acid recognition, here the crystal structure of human brain-type fatty acid-binding protein FABP7 complexed with palmitic acid (PA), a saturated fatty acid, is reported at a resolution of 1.6 A. Fatty Acids fatty acid binding protein 7 Homo sapiens
6 To better understand fatty acid recognition, here the crystal structure of human brain-type fatty acid-binding protein FABP7 complexed with palmitic acid (PA), a saturated fatty acid, is reported at a resolution of 1.6 A. Fatty Acids fatty acid binding protein 7 Homo sapiens
7 The PA bound to the fatty acid-binding pocket of FABP7 assumed a U-shaped conformation. Fatty Acids fatty acid binding protein 7 Homo sapiens
8 These results provide a better understanding of fatty acid recognition by FABP7 and expand the knowledge of the binding of PA to FABPs. Fatty Acids fatty acid binding protein 7 Homo sapiens