Pub. Date : 2021
PMID : 34193695
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Flavonoids are potential strikingly natural compounds with antioxidant activity and acetylcholinesterase (AChE) inhibitory activity for treating Alzheimer"s disease (AD). | Flavonoids | acetylcholinesterase (Cartwright blood group) | Homo sapiens |
| 2 | Flavonoids are potential strikingly natural compounds with antioxidant activity and acetylcholinesterase (AChE) inhibitory activity for treating Alzheimer"s disease (AD). | Flavonoids | acetylcholinesterase (Cartwright blood group) | Homo sapiens |
| 3 | In present study, in line with our interests in flavonoid derivatives as AChE inhibitors, a four-dimensional quantitative structure-activity relationship (4D-QSAR) molecular model was proposed. | Flavonoids | acetylcholinesterase (Cartwright blood group) | Homo sapiens |
| 4 | The molecular docking analysis was also carried out to understand exceedingly the interactions between flavonoids and the AChE targets, which was in good agreement with the 4D-QSAR model. | Flavonoids | acetylcholinesterase (Cartwright blood group) | Homo sapiens |
| 5 | Based on the information provided by the 4D-QSAR model and molecular docking analysis, the idea for optimizing the structures of flavonoids as AChE inhibitors was put forward which maybe provide theoretical guidance for the research and development of new AChE inhibitors. | Flavonoids | acetylcholinesterase (Cartwright blood group) | Homo sapiens |
| 6 | Based on the information provided by the 4D-QSAR model and molecular docking analysis, the idea for optimizing the structures of flavonoids as AChE inhibitors was put forward which maybe provide theoretical guidance for the research and development of new AChE inhibitors. | Flavonoids | acetylcholinesterase (Cartwright blood group) | Homo sapiens |