Title : Inhibiting PHGDH with NCT-503 reroutes glucose-derived carbons into the TCA cycle, independently of its on-target effect.

Pub. Date : 2021 Dec

PMID : 34192988






1 Functional Relationships(s)
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1 Incorporation of glucose-derived carbons entering the TCA cycle via pyruvate carboxylase was enhanced by NCT-503 treatment. Glucose pyruvate carboxylase Homo sapiens