Title : Increased exosome secretion in neurons aging in vitro by NPC1-mediated endosomal cholesterol buildup.

Pub. Date : 2021 Aug

PMID : 34183444






3 Functional Relationships(s)
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1 Increased exosome secretion in neurons aging in vitro by NPC1-mediated endosomal cholesterol buildup. Cholesterol NPC intracellular cholesterol transporter 1 Homo sapiens
2 We also show that the high number of ILVs is the consequence of the accumulation of cholesterol in MVBs, which in turn is due to decreased levels of the cholesterol extruding protein NPC1. Cholesterol NPC intracellular cholesterol transporter 1 Homo sapiens
3 We also show that the high number of ILVs is the consequence of the accumulation of cholesterol in MVBs, which in turn is due to decreased levels of the cholesterol extruding protein NPC1. Cholesterol NPC intracellular cholesterol transporter 1 Homo sapiens