Pub. Date : 2021 Sep
PMID : 34183377
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The inactivation of human aldehyde oxidase 1 by hydrogen peroxide and superoxide. | Superoxides | aldehyde oxidase 1 | Homo sapiens |
| 2 | Since hAOX1 and in particular some natural variants not only produce H2O2, but also high amounts of superoxide, we investigated the effect of both ROS molecules on the enzymatic activity of hAOX1 in more detail. | Superoxides | aldehyde oxidase 1 | Homo sapiens |
| 3 | Since hAOX1 and in particular some natural variants not only produce H2O2, but also high amounts of superoxide, we investigated the effect of both ROS molecules on the enzymatic activity of hAOX1 in more detail. | Superoxides | aldehyde oxidase 1 | Homo sapiens |
| 4 | We show that the inactivation of the hAOX1 wild type enzyme is mainly based on the production of hydrogen peroxide, while for the variant L438V both hydrogen peroxide and superoxide contribute to the time-dependent inactivation of the enzyme during turnover. | Superoxides | aldehyde oxidase 1 | Homo sapiens |