Title : Resveratrol attenuates retinal ganglion cell loss in a mouse model of retinal ischemia reperfusion injury via multiple pathways.

Pub. Date : 2021 Aug

PMID : 34181937






2 Functional Relationships(s)
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1 Furthermore, RES administration significantly suppressed the I/R injury-induced upregulation of the HIF-1a/VEGF and p38/p53 pathways, while activating the I/R injury-induced downregulation of the PI3K/Akt pathway. Resveratrol transformation related protein 53, pseudogene Mus musculus
2 CONCLUSIONS: Our data demonstrated that resveratrol can mitigate retinal ischemic injury induced RGC loss and retinal function impairment by inhibiting the HIF-1a/VEGF and p38/p53 pathways while activating the PI3K/Akt pathway. Resveratrol transformation related protein 53, pseudogene Mus musculus