Pub. Date : 2021 Oct
PMID : 34176192
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Sacituzumab govitecan (IMMU-132) is an antibody-drug conjugate that contains the irinotecan active metabolite, SN-38, linked to a humanized monoclonal antibody targeting trophoblast cell surface antigen 2 (Trop-2), which is overexpressed in many solid tumors. | Irinotecan | tumor associated calcium signal transducer 2 | Homo sapiens |
| 2 | IMPLICATIONS FOR PRACTICE: Sacituzumab govitecan (TRODELVY) is a novel antibody-drug conjugate composed of the active metabolite of irinotecan (SN-38) conjugated to a monoclonal antibody targeting Trop-2, an epithelial cell surface antigen overexpressed in many cancers. | Irinotecan | tumor associated calcium signal transducer 2 | Homo sapiens |
| 3 | IMPLICATIONS FOR PRACTICE: Sacituzumab govitecan (TRODELVY) is a novel antibody-drug conjugate composed of the active metabolite of irinotecan (SN-38) conjugated to a monoclonal antibody targeting Trop-2, an epithelial cell surface antigen overexpressed in many cancers. | Irinotecan | tumor associated calcium signal transducer 2 | Homo sapiens |