Title : Simultaneous quantification of twenty-eight components of Shenfu Injection in rat plasma by UHPLC-QQQ MS and its application to a pharmacokinetic study.

Pub. Date : 2021 Sep 5

PMID : 34171738






1 Functional Relationships(s)
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Protein Name
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1 Eight PPD-type ginsenosides Ra2, Ra3, Rb1, Ra1, Rc, Rb2, Rb3 and Rd presented relative high systemic exposure levels among ginsenosides with AUC0-t larger than 10,000 mug h/L, while mesaconine and hypaconine possessed relative high plasma abundance among aconite alkaloids with AUC0-t at 142.50 +- 17.42 mug h/L and 40.65 +- 5.61 mug h/L, respectively. Ginsenosides RB transcriptional corepressor 1 Rattus norvegicus