Pub. Date : 2021 Aug
PMID : 34165175
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The aim of the present study was to evaluate the combination of CAR T cells with the SINE compounds eltanexor and selinexor. | Eltanexor | nuclear receptor subfamily 1 group I member 3 | Homo sapiens |
| 2 | Due to CAR T-cell toxicity, sequential use of SINEs and CAR T cells was evaluated: Cytotoxicity of CAR T cells increased significantly when target cells were pre-treated with the SINE compound eltanexor. | Eltanexor | nuclear receptor subfamily 1 group I member 3 | Homo sapiens |
| 3 | In addition, exhaustion of CAR T cells decreased when target cells were pre-treated with eltanexor. | Eltanexor | nuclear receptor subfamily 1 group I member 3 | Homo sapiens |