Title : Direct P70S6K1 inhibition to replace dexamethasone in synergistic combination with MCL-1 inhibition in multiple myeloma.

Pub. Date : 2021 Jun 22

PMID : 34152396






1 Functional Relationships(s)
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1 Kinome analysis of dexamethasone-treated HMCLs revealed a reduction in serine/threonine peptide phosphorylation, which was predicted to result from reduced Akt activity. Dexamethasone AKT serine/threonine kinase 1 Homo sapiens