Title : Development of [18F]AldoView as the First Highly Selective Aldosterone Synthase PET Tracer for Imaging of Primary Hyperaldosteronism.

Pub. Date : 2021 Jul 8

PMID : 34137616






2 Functional Relationships(s)
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1 The purpose of this study was to synthesize a fluorine-18 labeled, highly selective aldosterone synthase (hCYP11B2) inhibitor, (18F)AldoView, and to assess its potential for the detection of aldosterone-producing adenomas (APAs) with positron emission tomography in patients with primary hyperaldosteronism (PHA). Fluorine-18 cytochrome P450 family 11 subfamily B member 2 Homo sapiens
2 The purpose of this study was to synthesize a fluorine-18 labeled, highly selective aldosterone synthase (hCYP11B2) inhibitor, (18F)AldoView, and to assess its potential for the detection of aldosterone-producing adenomas (APAs) with positron emission tomography in patients with primary hyperaldosteronism (PHA). Fluorine-18 cytochrome P450 family 11 subfamily B member 2 Homo sapiens